Primary Identifier | MGI:1889551 | Allele Type | Spontaneous |
Gene | Ph | Inheritance Mode | Semidominant |
Strain of Origin | STOCK Ph | Is Recombinase | false |
Is Wild Type | false |
description | Double heterozygotes of Phe with the closely linked genes KitW-v and Rw were different in color from those with Ph. In particular, Phe +/+ KitW-v mice resembled KitW-v homozygotes, and were sterile (J:5811). |
molecularNote | This allele comprises a deletion including the Pdgfra gene. Precise breakpoints have not been mapped, but does not extend into the coding sequences of the adjacent Kit gene. However, expression of a functional KIT protein is altered in these mutants. |