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Allele : Epas1<tm1Rus> endothelial PAS domain protein 1; targeted mutation 1, David W Russell

Primary Identifier  MGI:1861921 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Epas1
Transmission  Germline Strain of Origin  129S7/SvEvBrd
Is Recombinase  false Is Wild Type  false
molecularNote  A lacZ gene was inserted and fused in-frame into exon 2, and was followed by a neomycin selection cassette. Western blot analysis indicated that the expression of wild-type transcript was eliminated from this allele. However, a beta-galactosidase fusion protein was expressed under the control of the endogenous promoter.
  • mutations:
  • Insertion
  • synonyms:
  • HIF2alpha<LacZ>,
  • HIF2alpha<LacZ>,
  • Epas1<->,
  • Epas1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

22 Publication categories