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Publication : Rx-Cre, a tool for inactivation of gene expression in the developing retina.

First Author  Swindell EC Year  2006
Journal  Genesis Volume  44
Issue  8 Pages  361-3
PubMed ID  16850473 Mgi Jnum  J:111944
Mgi Id  MGI:3655186 Doi  10.1002/dvg.20225
Citation  Swindell EC, et al. (2006) Rx-Cre, a tool for inactivation of gene expression in the developing retina. Genesis 44(8):361-3
abstractText  Rx is a homeobox-containing gene that is critical for vertebrate eye development. Its expression domain delineates a field of cells from which the retina and the ventral hypothalamus develop. The 5' upstream regulatory sequences of the medaka fish Rx gene are functionally conserved during evolution to a degree that they direct gene expression into the Rx-expressing field of cells in mice. Using these sequences, we made a Cre line that can be used for inactivation of gene expression in the developing retina.
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