First Author | Swindell EC | Year | 2006 |
Journal | Genesis | Volume | 44 |
Issue | 8 | Pages | 361-3 |
PubMed ID | 16850473 | Mgi Jnum | J:111944 |
Mgi Id | MGI:3655186 | Doi | 10.1002/dvg.20225 |
Citation | Swindell EC, et al. (2006) Rx-Cre, a tool for inactivation of gene expression in the developing retina. Genesis 44(8):361-3 |
abstractText | Rx is a homeobox-containing gene that is critical for vertebrate eye development. Its expression domain delineates a field of cells from which the retina and the ventral hypothalamus develop. The 5' upstream regulatory sequences of the medaka fish Rx gene are functionally conserved during evolution to a degree that they direct gene expression into the Rx-expressing field of cells in mice. Using these sequences, we made a Cre line that can be used for inactivation of gene expression in the developing retina. |