| First Author | Qiu HY | Year | 2008 |
| Journal | Genesis | Volume | 46 |
| Issue | 6 | Pages | 324-8 |
| PubMed ID | 18543300 | Mgi Jnum | J:136677 |
| Mgi Id | MGI:3796776 | Doi | 10.1002/dvg.20399 |
| Citation | Qiu HY, et al. (2008) Pitx3-CreER mice showing restricted Cre expression in developing ocular lens and skeletal muscles. Genesis 46(6):324-8 |
| abstractText | To generate temporally controlled inactivation or activation of interested genes in Pitx3-expressing cells, the tamoxifen-inducible form of Cre, CreER(T2), was inserted into the Pitx3 locus of a mouse BAC clone. Following a single dose of tamoxifen, Cre activity in Pitx3-CreER(T2) transgenic mice was observed in the ocular lens and skeletal muscles but not in the central nervous system at various embryonic stages. This mouse line provides a reagent for driving inducible Cre-dependent recombination in the lens and skeletal muscles during embryonic development. |
