| First Author | Durieux PF | Year | 2009 |
| Journal | Nat Neurosci | Volume | 12 |
| Issue | 4 | Pages | 393-5 |
| PubMed ID | 19270687 | Mgi Jnum | J:150475 |
| Mgi Id | MGI:3850813 | Doi | 10.1038/nn.2286 |
| Citation | Durieux PF, et al. (2009) D2R striatopallidal neurons inhibit both locomotor and drug reward processes. Nat Neurosci 12(4):393-5 |
| abstractText | The specific functions of dopamine D(2) receptor-positive (D(2)R) striatopallidal neurons remain poorly understood. Using a genetic mouse model, we found that ablation of D(2)R neurons in the entire striatum induced hyperlocomotion, whereas ablation in the ventral striatum increased amphetamine conditioned place preference. Thus D(2)R striatopallidal neurons limit both locomotion and, unexpectedly, drug reinforcement. |
