| First Author | Yun SW | Year | 2007 |
| Journal | Biochem Biophys Res Commun | Volume | 360 |
| Issue | 3 | Pages | 520-4 |
| PubMed ID | 17612503 | Mgi Jnum | J:122997 |
| Mgi Id | MGI:3716227 | Doi | 10.1016/j.bbrc.2007.05.227 |
| Citation | Yun SW, et al. (2007) beta-Amyloid deposition and prion infection in adult primary brain cell long-term culture model. Biochem Biophys Res Commun 360(3):520-4 |
| abstractText | We report an in vitro model of the adult central nervous system produced by culturing primary brain cells isolated from adult mice for periods longer than 4 months. We applied this novel cell culture method to model progressive neurodegenerative diseases. After long-term culture of adult primary brain cells prepared from Alzheimer's disease and prion disease mouse models, we observed beta-amyloid deposition and prion infection in primary cell cultures in vitro. |
