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Allele : Pak2<Gt(OST104058)Lex> p21 (RAC1) activated kinase 2; gene trap OST104058, Lexicon Genetics

Primary Identifier  MGI:1861800 Allele Type  Gene trapped
Attribute String  Null/knockout Gene  Pak2
Transmission  Germline Strain of Origin  129S5/SvEvBrd
Is Recombinase  false Is Wild Type  false
Project Collection  Lexicon
molecularNote  The gene trap cassette consisting of an long terminal repeat (LTR), splice acceptor sequence (SA), internal ribosome entry site-galactosidase/neomycin phosphotransferase fusion gene (IRES-geo), polyadenylation sequence, phosphoglycerate kinase-1 promoter (PGK), puromycin N-acetyltransferase gene, splice donor sequence (SD), and LTR, inserted before exon 2. Western blot analysis indicates that levels of protein in the hippocampus and cortex are reduced in heterozygotes.
  • mutations:
  • Insertion of gene trap vector
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories