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Allele : Cd38<tm1Lnd> CD38 antigen; targeted mutation 1, Frances E Lund

Primary Identifier  MGI:1861803 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cd38
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced a genomic fragment containing exons 2 and 3, which encode the putative active site of the encoded protein. Homozygous mice lacked transcripts derived from this allele (data not shown). Flow cytometry analysis on splenocytes derived from homozygous mice confirmed that no detectable protein was expressed on the cell surface.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • CD38<null>,
  • CD38-,
  • Cd38<tm1Lud>,
  • CD38<null>,
  • CD38-,
  • Cd38<tm1Lud>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

5 Carried By

0 Driven By

94 Publication categories