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Allele : Cd86<tm1Shr> CD86 antigen; targeted mutation 1, Arlene H Sharpe
Primary Identifier  MGI:1861805 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cd86
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced an exon encoding the IgV-like domain of the protein and flanking genomic sequences. FACS analysis on splenocytes and LPS-stimulated B cells derived from homozygous mice confirmed that no functional protein was encoded by this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • B7-2-,
  • B7-2-,
  • B7.2 KO,
  • B7.2 KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

11 Carried By

0 Driven By

79 Publication categories





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