| Help | About | Contact Us

Allele : Cdkn1c<tm1Sje> cyclin dependent kinase inhibitor 1C; targeted mutation 1, SJ Elledge

Primary Identifier	MGI:1861811	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Cdkn1c
Inheritance Mode	Recessive	Transmission	Germline
Strain of Origin	129S7/SvEvBrd-Hprt1<b-m2>	Is Recombinase	false
Is Wild Type	false

molecularNote

Replacement of exons 1 and 2 (87% of the Cdkn1c coding region) with a neomycin cassette.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
p57<->,
Cdkn1c<->,
p57<+/-m>,
p57<KIP2>,
p57<KIP2>,
p57<->,
Cdkn1c<->,
p57<+/-m>

earliestPublication:
Zhang P, et al. (1997) Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith-Wiedemann syndrome. Nature 387(6629):151-8

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

37 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=74157202

MouseMine