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Allele : Tg(FGF7)2Efu transgene insertion 2, Elaine Fuchs
Primary Identifier  MGI:1926467 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(FGF7)2Efu
Inheritance Mode  Not Specified Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
description  Founder number 2 is representative of a number of founders that exhibit perinatal lethality at birth to postnatal day 1. These founder numbers were designated 2, 4, 5, 6, 7, 8, 9, 12, and 13. Due to lethality, no mouse lines were established.

See Tg(FGF7)11Efu and Tg(FGF7)29Efu for variability in phenotypes using this construct.
molecularNote  Overexpression of the human FGF7 gene in basal cells of stratified squamous epithelia driven by the human K14 (KRT14) promoter.
  • mutations:
  • Insertion
  • synonyms:
  • KGF-NB2,
  • K14-KGF,
  • K14-KGF,
  • KGF-NB2
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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