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Allele : Xrcc4<tm1Fwa> X-ray repair complementing defective repair in Chinese hamster cells 4; targeted mutation 1, Frederick W Alt

Primary Identifier  MGI:1926771 Allele Type  Targeted
Attribute String  Null/knockout Gene  Xrcc4
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Replacement of sequence encoding exon 3 of the Xrcc4 gene with a loxP-flanked neomycin cassette. This cassette was then removed by crossing mice with germline-Cre expressing mice to generate this allele containing a deletion of exon 3. Any potential transcript from this allele that spliced from exon 2 to exon 4 or 5 would harbor a frameshift mutation.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • XRCC4-,
  • XRCC4-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

26 Publication categories