First Author | Tsuda M | Year | 2009 |
Journal | FEBS Lett | Volume | 583 |
Issue | 8 | Pages | 1319-22 |
PubMed ID | 19303874 | Mgi Jnum | J:147986 |
Mgi Id | MGI:3843122 | Doi | 10.1016/j.febslet.2009.03.030 |
Citation | Tsuda M, et al. (2009) Induction of gene encoding FABP4 in Pten-null keratinocytes. FEBS Lett 583(8):1319-22 |
abstractText | Keratinocyte-specific Pten-null mice revealed distinct phenotypes, including epidermal and sebaceous gland hyperplasia. To determine the candidate genes that contribute to their phenotypes, we analyzed a comprehensive gene expression of Pten-null keratinocytes using microarray technology. Consequently, it was demonstrated that the most induced gene was adipocyte-specific fatty acid-binding protein (FABP4). Collectively, it is conceivable that the FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. |