Primary Identifier | MGI:1928830 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Nrg1 |
Inheritance Mode | Recessive | Transmission | Germline |
Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Specific disruption of the intracellular domain of the Nrg1 gene. A stop codon and a poly(A) sequence was introduced immediately 3' to the coding region for the first three amino acids of the intracellular domain, followed by a neomycin cassette. |