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Allele : Msx2<tm1Rilm> msh homeobox 2; targeted mutation 1, Richard Maas

Primary Identifier	MGI:1926381	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Msx2
Inheritance Mode	Recessive	Transmission	Germline
Strain of Origin	129S4/SvJae	Is Recombinase	false
Is Wild Type	false

description	Phenotypic Similarity to Human Syndrome: Peters anomaly in homozygous mice (J:184697)
molecularNote	Gene disruption caused by insertion of a pMC1-neo cassette into coding sequences located just 5' to the homeobox domain in exon 2.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Msx2-,
Msx2-

earliestPublication:
St Amand TR, et al. (2000) Antagonistic signals between BMP4 and FGF8 define the expression of Pitx1 and Pitx2 in mouse tooth-forming anlage. Dev Biol 217(2):323-32

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

35 Publication categories

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