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Allele : Tg(Trp53R172H)8512Jmr transgene insertion 8512, Jeffrey Rosen

Primary Identifier  MGI:1929642 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Trp53R172H)8512Jmr
Strain of Origin  FVB Is Recombinase  false
Is Wild Type  false
description  On an FVB/N background transgenic mice express TRP53 with both dominant-negative and a gain-of function properties.
molecularNote  This transgene contains the rat whey acidic protein promoter and an allele of the mouse Trp53 mini-gene that carries a point mutation in codon 172 (CGC->CAC; Arg172His).
  • mutations:
  • Insertion
  • synonyms:
  • Wap-p53<R172H>,
  • 172R-H,
  • Wap-p53<R172H>,
  • 172R-H,
  • p53-172H,
  • p53-172H,
  • p53(R172H),
  • p53(R172H)
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

5 Carried By

0 Driven By

17 Publication categories