Primary Identifier | MGI:1929642 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Trp53R172H)8512Jmr |
Strain of Origin | FVB | Is Recombinase | false |
Is Wild Type | false |
description | On an FVB/N background transgenic mice express TRP53 with both dominant-negative and a gain-of function properties. |
molecularNote | This transgene contains the rat whey acidic protein promoter and an allele of the mouse Trp53 mini-gene that carries a point mutation in codon 172 (CGC->CAC; Arg172His). |