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Allele : Tg(BMP4)6Blh transgene insertion 6, Brigid L Hogan

Primary Identifier  MGI:1926357 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(BMP4)6Blh
Inheritance Mode  Not Specified Strain of Origin  (C57BL/6 x DBA/2)F1
Is Recombinase  false Is Wild Type  false
description  Allele Notes: Thirteen founder mice were obtained using this transgene construct, but only line 6 was fertile and used in most experiments. Founders 1-5 displayed a severe phenotype that included cranifacial abnormalies and died perinatally. Founders 6-11 had a more moderate phenotype and are described in the paper. Founders 12 and 13 did not express the transgene.
molecularNote  Overexpression of the human BMP4 gene in nasal epithelium, oral mucosa, and the outer root sheath of hair and whisker follicles under the control of the bovine cytokeratin IV* promoter.
  • mutations:
  • Insertion
  • synonyms:
  • TgCK4-6,
  • TgCK4-6
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories