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Allele : Vegfa<tm2Gne> vascular endothelial growth factor A; targeted mutation 2, Genentech

Primary Identifier	MGI:1931048	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Vegfa
Transmission	Germline	Strain of Origin	129/Sv
Is Recombinase	false	Is Wild Type	false

molecularNote

Insertion of a loxP-flanked neomycin cassette and a loxP site flanking exon 3. This mutation had no effect on the secretion of the protein.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
VEGF<lox>,
VEGFloxP(-),
VEGF<lox>,
VEGFloxP(-),
VEGF<+f>,
Vegf-A/loxP,
VEGFloxP,
VEGFloxP,
VEGF<Flox>,
VEGF<Flox>,
VEGF<+f>,
Vegf-A/loxP

earliestPublication:
Gerber HP, et al. (1999) VEGF is required for growth and survival in neonatal mice. Development 126(6):1149-59

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

153 Publication categories

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