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Allele : Xrcc1<tm1Rpe> X-ray repair complementing defective repair in Chinese hamster cells 1; targeted mutation 1, Roger A Pedersen

Primary Identifier  MGI:1932097 Allele Type  Targeted
Attribute String  Null/knockout Gene  Xrcc1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Insertion of a neomycin resistance cassette into exon 8 disrupted the Xrcc1 gene and replaced 8bp of coding sequence. Western blot analysis did not detect XRCC1 protein or truncation products in total protein extracts from cell lines made from 8.5 day embryos that were homozygous for both Xrcc1tm1Rpe and Trp53tm1Tyj.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Xrcc1-,
  • Xrcc1-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

7 Publication categories