Primary Identifier | MGI:1932522 | Allele Type | Targeted |
Attribute String | Null/knockout, Recombinase | Gene | Foxg1 |
Inheritance Mode | Recessive | Transmission | Germline |
Strain of Origin | 129P2/OlaHsd-Hprt1<b-m3> | Is Recombinase | true |
Is Wild Type | false |
description | Cre mediated recombination was demonstrated in 3 reporter mouse lines in the following tissues: telencephalon, anterior optic vesicle, otic vesicle, facial and head ectoderm, olfactory epithelium, mid-hindbrain junction, and pharyngeal pouches. |
molecularNote | Most of the coding region was replaced with a cre gene and a neomycin cassette. The cre gene sequence was fused in-frame following the first 13 codons of the gene. The endogenous promoter is active in telencephalon, anterior optic vesicle, otic vesicle, facial and head ectoderm, olfactory epithelium, mid-hindbrain junction and pharyngeal pouches. |