Primary Identifier | MGI:1934348 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Pax6 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Insertion of loxP sequences flanking the exons encoding the amino terminus of the protein, including the initiator methionine and most of the paired domain. A frt-flanked neomycin cassette in intron 6 was removed via Flp-mediated recomination to create the final allele. These insertions had no effect on the normal function of the allele. |