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Allele : Brca1<tm1Cxd> breast cancer 1, early onset; targeted mutation 1, Chu-Xia Deng

Primary Identifier	MGI:1930612	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Brca1
Transmission	Germline	Strain of Origin	129S6/SvEvTac
Is Recombinase	false	Is Wild Type	false

molecularNote

Deletion of 330 bp of intron 10 and 407 bp of exon 11 and replacement with a neomycin cassette.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
Brca1<11->,
Brca1<Ko>,
Brca1<delta11>,
brca1<Ko22>,
Brca1<delta11>,
Brca1<Ko>,
brca1<Ko22>,
Brca1<11->

earliestPublication:
Shen SX, et al. (1998) A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability. Oncogene 17(24):3115-24

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

25 Publication categories

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