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Allele : Brca2<tm1Cam> breast cancer 2, early onset; targeted mutation 1, University of Cambridge

Primary Identifier  MGI:1930616 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Brca2
Transmission  Germline Strain of Origin  129S/SvEv
Is Recombinase  false Is Wild Type  false
molecularNote  Insertion of a beta-geo selection cassette into exon 11 and deletion of nucleotides 4668-4989. This allele expresses a truncated protein at amino acid 1492, similar to truncating mutations found in humans.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Brca2<Tr>,
  • Brca2<Tr>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

9 Publication categories