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Allele : Fgfr3<tm1Dor> fibroblast growth factor receptor 3; targeted mutation 1, David M Ornitz

Primary Identifier  MGI:1931521 Allele Type  Targeted
Attribute String  Null/knockout Gene  Fgfr3
Inheritance Mode  Recessive Transmission  Germline
Strain of Origin  129S6/SvEvTac Is Recombinase  false
Is Wild Type  false
molecularNote  A neomycin cassette replaced 3 kb of sequence that encodes the Ig-like domain II through the transmembrane domain. RNAase protection analysis on samples derived from homozygous mutant adult brain indicates that this allele produces an aberrant transcript. However, any translation product produced would be unable to bind ligand and is predicted not to be transported to the cell surface.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Fgfr3 -,
  • Fgfr3 -
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

0 Driven By

36 Publication categories