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Allele : Shc3<tm1Paw> src homology 2 domain-containing transforming protein C3; targeted mutation 1, Tony Pawson

Primary Identifier	MGI:1933356	Allele Type	Targeted
Attribute String	Null/knockout, Reporter	Gene	Shc3
Transmission	Germline	Strain of Origin	(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

Insertion of an IRES-LacZ cassette disrupted the Shc3 gene. SHC3 antibodies did not detect protein in 4 week old homozygous mutant brain.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
ShcC-,
Rai<->,
Rai<->,
ShcC-

earliestPublication:
Sakai R, et al. (2000) The mammalian ShcB and ShcC phosphotyrosine docking proteins function in the maturation of sensory and sympathetic neurons. Neuron 28(3):819-33

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

13 Publication categories

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