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Allele : Hfe<tm1Gfn> homeostatic iron regulator; targeted mutation 1, Susan Gilfillan

Primary Identifier  MGI:1934013 Allele Type  Targeted
Attribute String  Null/knockout Gene  Hfe
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  2.5 kb of sequence containing the second and third exons, which encode the alpha1 and alpha2 putative ligand binding domains, were replaced with a floxed PGK neomycin selection cassette. Northern blots prepared with total RNA isolated from kidney and liver tissue did not detect full length mRNA in homozygous mutant mice.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Hfe<0>,
  • Hfe<0>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

32 Publication categories