Primary Identifier | MGI:1934023 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Trpv1 |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene was disrupted by deleting an exon encoding part of the fifth and all of the sixth putative transmembrane domains of the channel, together with the intervening pore-loop region. Northern blot analysis showed that mRNA derived from dorsal root ganglia (DRG) of homozygous mice lacked detectable transcripts encoded by this allele. |