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Allele : Trpv1<tm1Jul> transient receptor potential cation channel, subfamily V, member 1; targeted mutation 1, David Julius

Primary Identifier  MGI:1934023 Allele Type  Targeted
Attribute String  Null/knockout Gene  Trpv1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was disrupted by deleting an exon encoding part of the fifth and all of the sixth putative transmembrane domains of the channel, together with the intervening pore-loop region. Northern blot analysis showed that mRNA derived from dorsal root ganglia (DRG) of homozygous mice lacked detectable transcripts encoded by this allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Vr1<tm1Jul>,
  • Trpv-1<->,
  • Trpv-1<->,
  • TRPV1-KO,
  • TRPV1-KO,
  • Vr1<tm1Jul>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

368 Publication categories