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Allele : Soat1<tm1Ishi> sterol O-acyltransferase 1; targeted mutation 1, Shun Ishibashi

Primary Identifier  MGI:1934032 Allele Type  Targeted
Attribute String  Null/knockout Gene  Soat1
Transmission  Germline Strain of Origin  129S7/SvEvBrd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced 4 kb of sequence encoding the first transmembrane domain and a conserved serine. Northern blot analyses of homozygous mutant mice did not detect any transcripts in macrophages, adrenal glands, ovaries and testes. Western blot analyses of macrophages, adrenal glands, ovaries, and testes did not detect the protein in homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • ACAT-1,
  • ACAT-1
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories