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Allele : Mgp<tm1Kry> matrix Gla protein; targeted mutation 1, Gerard Karsenty

Primary Identifier  MGI:1934912 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mgp
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
description  Phenotypic Similarity to Human Syndrome: Singleton-Merten Syndrome in homozygous mice (J:38867)
molecularNote  A neomycin resistance cassette replaced a 3.4 kb fragment of the gene containing the proximal promoter, exons 1, 2, 3, and most of 4. Northern blots of RNA from lungs of homozygous mutant mice showed no detectable transcript for the targeted protein.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • MGP-,
  • mgp<m1>,
  • MGP-,
  • mgp<m1>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

33 Publication categories