Primary Identifier | MGI:1934912 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Mgp |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
description | Phenotypic Similarity to Human Syndrome: Singleton-Merten Syndrome in homozygous mice (J:38867) |
molecularNote | A neomycin resistance cassette replaced a 3.4 kb fragment of the gene containing the proximal promoter, exons 1, 2, 3, and most of 4. Northern blots of RNA from lungs of homozygous mutant mice showed no detectable transcript for the targeted protein. |