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Allele : Psen1<tm1Pcw> presenilin 1; targeted mutation 1, Philip C Wong
Primary Identifier  MGI:1930934 Allele Type  Targeted
Attribute String  Null/knockout Gene  Psen1
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced 1.9kb of sequence containing the second coding exon. Immunoblot analysis using antibodies specific for epitopes contained within each of the endoproteolytic products of the gene did not detect protein in SDS extracts of homozygous mutant E18.5 embryos.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • PS1<->,
  • PS1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

43 Publication categories





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