| First Author | Geys L | Year | 2015 |
| Journal | Cell Immunol | Volume | 298 |
| Issue | 1-2 | Pages | 33-6 |
| PubMed ID | 26344897 | Mgi Jnum | J:233644 |
| Mgi Id | MGI:5787744 | Doi | 10.1016/j.cellimm.2015.08.006 |
| Citation | Geys L, et al. (2015) CD36 deficiency blunts effects of diet on regulatory T cells in murine gonadal adipose tissue and mesenteric lymph nodes. Cell Immunol 298(1-2):33-6 |
| abstractText | The effect of cluster of differentiation (CD)36 on regulatory T cells (Treg) was investigated in gonadal (GN) adipose tissues and mesenteric lymph nodes (MLN) of wild-type (WT) and CD36 deficient (CD36(-/-)) mice kept on standard fat (SFD, lean) or on high fat diet (HFD, obese). GN adipose tissue mass was smaller, but MLN size larger for obese CD36(-/-) versus obese WT mice. Overall, the reduction of Treg cells in GN adipose tissue and MLN after a HFD is much more prominent in WT than CD36(-/-) mice. Moreover, CD36(-/-) mice may be protected against obesity-related chronic inflammation. |
