Primary Identifier | MGI:2445979 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Hoxd |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Region IX, located in the intergenic region between Hoxd11 and Hoxd10, was disrupted by a 7 nt mutation in a nuclear receptor response element (NRRE). A floxed neo cassette that was included in the targeting construct was removed in vitro via cre mediated recombination, leaving a single loxP site downstream of region IX. |