| Primary Identifier | MGI:1931860 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Ncoa3 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A TGK-neomycin resistance cassette replaced sequences spanning exon 2 through exon 13. The cassette introduced a lacZ sequence in frame with the endogenous promoter. The authors predict that the targeted allele would not produce a functional protein, but would produce a beta-galactosidase fusion protein controlled by the endogenous promoter. Western analysis did not detect wild-type protein in lactating mammary glands of homozygous mutant mice. |
