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Allele : Pou2af1<tm1Rgr> POU domain, class 2, associating factor 1; targeted mutation 1, Robert Roeder

Primary Identifier  MGI:1931863 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pou2af1
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
description  ES cell line = E14 (129P2/OlaHsd) or CJ7 (129S1/Sv-p+ Tyr+ Kitl+).
molecularNote  A PGK-neomycin resistance cassette replaced exons 2, 3, and 4. Northern blot analysis on spleen RNA from homozygous mice confirmed that no mRNA was expressed from this allele and immunoblot analysis on bone marrow derived cell lines from homozygous mice demonstrated an absence of encoded protein.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • OCA-B-,
  • OCA-B-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

17 Publication categories