Primary Identifier | MGI:1931879 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Vim |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 1 of the Vim gene was disrupted by insertion of a neomycin resistance cassette. Northern analysis of homozygous mutant animals did not detect Vim transcript in lung and spleen, but did detect a minor aberrant transcript in heart. Western analysis and immunofluorescence microsopy did not detect VIM protein in tissues of homozygous mutant mice. |