Primary Identifier | MGI:1933715 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cr2 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Insertion of a neomycin resistance cassette into short consensus repeat (SCR) 10 disrupted the gene by introducing a frameshift mutation and a stop codon. Immunohistochemical staining and flow cytometric analysis detected negligible expression in splenic B cells of homozygous mutant mice. |