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Allele : Ncf1<tm1Shl> neutrophil cytosolic factor 1; targeted mutation 1, Steven M Holland

Primary Identifier	MGI:1934143	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Ncf1
Transmission	Germline	Strain of Origin	129S2/SvPas
Is Recombinase	false	Is Wild Type	false

molecularNote

Insertion of a neomycin resistance cassette into exon 7 disrupted the gene. The region in the human ortholog that corresponds to exon 7 is known to be necessary for gene function.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
p47phox-,
p47phox-,
p47<phox>-,
p47<phox>-,
p47<phox->,
p47<phox->

earliestPublication:
Jackson SH, et al. (1995) The p47phox mouse knock-out model of chronic granulomatous disease. J Exp Med 182(3):751-8

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

111 Publication categories

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