| Primary Identifier | MGI:1935192 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Abca1 |
| Transmission | Germline | Strain of Origin | DBA/1LacJ |
| Is Recombinase | false | Is Wild Type | false |
| description | When used in bone marrow transplant into Ldlrtm1Her homozygous mice, Abca1tm1Jdm Abcg1tm1Dgen homozygous cells accelerate the development of atherosclerosis. (J:130777) |
| molecularNote | A 5.7 kb genomic fragment containing exons 17-22 was deleted and replaced with a neomycin selection cassette. These sequences correspond to amino acids 788 to 1093 of the encoded protein. RT-PCR analysis on RNA derived from liver demonstrated that no detectable transcript was produced from this allele in homozygous mice. |
