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Allele : Tnc<tm1Ref> tenascin C; targeted mutation 1, Reinhard Fassler

Primary Identifier  MGI:2148541 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tnc
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced a NcoI genomic fragment in exon 2 that contained sequences encoding the signal peptide and the heptad repeat sequences. RT-PCR analysis demonstrated the presence of a shorter aberrant transcript in homozygous mice, but no protein was detectable by Western blot analysis in pooled extracts of cerebellum, lung and thymus.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

35 Publication categories

Trail: Allele