| Primary Identifier | MGI:2148541 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Tnc |
| Transmission | Germline | Strain of Origin | 129S2/SvPas |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin resistance cassette replaced a NcoI genomic fragment in exon 2 that contained sequences encoding the signal peptide and the heptad repeat sequences. RT-PCR analysis demonstrated the presence of a shorter aberrant transcript in homozygous mice, but no protein was detectable by Western blot analysis in pooled extracts of cerebellum, lung and thymus. |