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Allele : Egfr<tm1Wag> epidermal growth factor receptor; targeted mutation 1, Erwin F Wagner

Primary Identifier  MGI:1935108 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Egfr
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  Part of the first exon was replaced by an in frame lacZ gene, followed by either a neomycin or a hygromycin selection cassette. These two different constructs were used to generate separate lines of mice, but the analysis did not distinguish between them. An EGFR-beta-galactosidase fusion protein was produced from this allele that was expressed under the control of the endogenous gene promoter.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • EGFR-,
  • EGFR-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

14 Publication categories