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Allele : Dmd<tm1Ndl> dystrophin, muscular dystrophy; targeted mutation 1, Uri Nudel

Primary Identifier  MGI:2148260 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Dmd
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Most of the unique unnumbered first exon encoding the shorter alternative splice transcript Dp71 was replaced with a promoterless Betageo gene. This exon is located in intron 62 of the Dmd gene. Western blot analysis confirmed the specific inactivation of the alternative splice product Dp71 without affecting the expression of any other DMD isoforms.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Dp71-null,
  • Dp71<->,
  • Dp71-null,
  • Dp71<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

22 Publication categories