| Primary Identifier | MGI:2150347 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Fgf8 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd-Hprt1<b-m3> |
| Is Recombinase | false | Is Wild Type | false |
| description | One of three alleles produced using a targeting construct capable of inducing different allelic variants when mated to mice that express cre, flp, or both. Referred to in the literature as Fgf8flox, Flp mediated recombinase reverts the hypomorphic Fgf8neo allele to wild-type (J:45909). |
| molecularNote | This allele is a derivative of Fgf8tm1.1Mrt in which mice carrying this allele were mated to beta-actin Flp mice, which resulted in heterozygous offspring carrying a recombined Fgf8 allele in which the neomycin resistance cassette was deleted, and exons 2 and 3 remained flanked by loxP sites. |
