| First Author | Ing R | Year | 2005 |
| Journal | Infect Immun | Volume | 73 |
| Issue | 5 | Pages | 3172-7 |
| PubMed ID | 15845528 | Mgi Jnum | J:97620 |
| Mgi Id | MGI:3575950 | Doi | 10.1128/IAI.73.5.3172-3177.2005 |
| Citation | Ing R, et al. (2005) Interleukin-15 enhances innate and adaptive immune responses to blood-stage malaria infection in mice. Infect Immun 73(5):3172-7 |
| abstractText | Compared to C57BL/6 wild-type mice, interleukin-15(-/-) (IL-15(-/-)) mice showed delayed clearance of Plasmodium chabaudi AS infection, lower type 1 cytokine production, impaired dendritic cell and NK cell functions, and lower titers of malaria-specific antibodies. Thus, IL-15 supports early control and timely resolution of blood-stage malaria through promotion of Th1-dependent innate and adaptive immune responses. |
