| Primary Identifier | MGI:2137850 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Ptger4 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| description | Phenotypic Similarity to Human Syndrome: Patent Ductus Arteriosus in homozygous mice (J:44108) |
| molecularNote | Exons 1 and 2, which encode the initiation codon and regions of the gene encoding six of the seven transmembrane-spanning domains and putative extracellular loops, were replaced by a neomycin resistance gene. Northern blot analysis of RNA from thymus and spleen of homozygous mutant neonates using cDNA probes specific for this gene verified the loss of expression. |
