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Allele : Tcf21<tm1Jrt> transcription factor 21; targeted mutation 1, Janet Rossant

Primary Identifier	MGI:2148207	Allele Type	Targeted
Attribute String	Null/knockout, Reporter	Gene	Tcf21
Transmission	Germline	Strain of Origin	(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

Replacement of the initiation codon and sequences encoding the bHLH domain with an in-frame lacZ gene and neomycin resistance cassette.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
pod1/lacZ,
Tcf21<LacZ>,
pod1<->,
Tcf21<LacZ>,
pod1/lacZ,
pod1<->

earliestPublication:
Quaggin SE, et al. (1999) The basic-helix-loop-helix protein pod1 is critically important for kidney and lung organogenesis. Development 126(24):5771-83

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

15 Publication categories

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