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Allele : Gnas<tm1Gwa> GNAS complex locus; targeted mutation 1, Gary Wand
Primary Identifier  MGI:2152744 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gnas
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced 0.5kb of sequence containing the ATG codon and extending through an NruI site in intron 1. Quantitative immunoblot studies showed protein levels in multiple brain regions of mice heterozygous for this allele were significantly reduced relative to wild-type.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Gnas<E1->,
  • Gnas<E1->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

10 Publication categories





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