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Allele : Aqp3<tm1Ask> aquaporin 3; targeted mutation 1, Alan S Verkman

Primary Identifier  MGI:2150021 Allele Type  Targeted
Attribute String  Null/knockout Gene  Aqp3
Transmission  Germline Strain of Origin  C57BL/6J x (Rb(11.16)2H x Rb(16.17)32Lub)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A 1.3kb neomycin resistance cassette replaced parts of exons 2 and 3 of the gene. Northern blots of kidneys from homozygous mutant mice had no detectable Aqp3 transcript. Immunofluorescence analysis of fixed frozen kidney sections from homozygous mutant mice had no detectable Aqp3 protein.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • AQP3-,
  • AQP3-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

40 Publication categories