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Allele : Gna11<tm1Soff> guanine nucleotide binding protein, alpha 11; targeted mutation 1, Stefan Offermanns

Primary Identifier  MGI:2151589 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gna11
Transmission  Germline Strain of Origin  129S7/SvEvBrd
Is Recombinase  false Is Wild Type  false
description  ES cell line = AB1 (129S7/SvEvBrd-Hprt+) or JH1 (129S7/SvEvBrd).
molecularNote  A neomycin cassette replaced exons 3, 4 and part of 5, which encodes the amino acids that contribute to the guanine nucleotide binding pocket. Western blot analysis on extracts of brain, spleen and testis tissues did not detect any protein expressed from this allele in homozyogous mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Gna11<->,
  • Galpha11-,
  • Galpha11-,
  • Gna11<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

70 Publication categories